World’s Best Food Supplement for Chronic Fatigue… Tre-en-en

September 9, 2012

in BLOGS,Energy,General,Nutritionals,Pro Vitality with Formula IV® Plus

The world’s best food supplement for chronic fatigue… Tre-en-en… is a well researched and proven grain oil supplement. It is unique to the food supplement industry. Let me tell you the story behind the development of Tre-en-en and what makes it so special that I can be bold about calling it the world’s best food supplement for chronic fatigue (and good health.)
I have been asked many times “What are essential oils from grains?” This article is my attempt at answering that all important question.
As you know from following my blog, I have written about the processing of grains and how it has affected our health. Removal of the essential oils from grains allowed for a longer shelf life. This process stripped the grains of most nutritional value and left them as an unbalanced food source. This happened over a period of time so people gradually became depleted of these essential oils. Symptoms such as extreme fatigue and arthritis were being suffered by more and more of the population.
Refining and removal of the essential oils from the heart of the wheat set the stage for widespread malnutrition. The bran of rice started being removed about the same time the refining of wheat was perfected. White rice caused epidemics of beriberi in the orient. Another less known fact is that the removal of the outer hull of the soybean is the source of very valuable nutrition. Most products made from soy such as tofu are missing this important nutrient of the soybean.
Generations of people were soon complaining of fatigue and exhaustion. They were the children and grandchildren of people who had sawed forests and dug ditches by hand. They knew something was wrong but yet the doctors couldn’t find anything wrong with them.
In 1946 a government research grant was awarded to Hollywood Presbyterian Hospital in southern California to study these chronically fatigued people. As a result of the research, a formula was developed of the essential oils (lipids and sterols) from wheat, rice, and soy. The chronically fatigued people participating in the study improved greatly when these essential grain oils were added back into their daily diet.
‘Tre-en-en’ was the name given to these concentrated extracts of lipids and sterols from the wheat, rice, and soy. Tre-en-en is Greek for ‘three-in-one.’
As happens when many government studies end, the formula was put on a shelf and nothing was done with it. This was sad as many people were being helped by these essential oils.
One of the participants in the study was a woman who had suffered for years with extremely painful rheumatoid arthritis. Her pain was so bad she could not stand the pressure of sheets on her bed at night. Her husband, Wally heard about the research going on in southern California. He quit his job and started working as a medical detail man with the doctors who were doing the grain oil research. His wife became one of the study patients and improved dramatically over the next 2 years.
When the grain oil formula was put on the shelf, the man and his wife were able to acquire the formula from the research hospital. In 1958 Wally joined with Don Pickett, a salesman for a direct sales company that sold waterless cookware. They founded the Neo-Life Company. Wally attempted to make the formula available to the medical community for their patients but unfortunately the medical community was not interested. Soon Wally became discouraged and stepped away from the company.
Mr. Pickett, being familiar with direct sales marketing, chose to use direct sales as his marketing tool because he knew the product would require explanation. People would need to understand the difference between his supplement and other supplements on the market. The first and only product he sold with the brand name of Neo-Life was Formula IV. Formula IV contained the grain oil formula plus additional vitamins, minerals, amino acids (protein), and enzymes derived from whole foods.
‘The Chain of Life’ was used as a tool to market Formula IV because it was the first supplement ever to contain all the nutrients involved in the complete chain of life. A chain is only as strong as its weakest link.
Mr. Pickett’s very first customer was Fred whose wife, Jeanne (in her late 30’s) was pretty well bed-ridden with rheumatoid arthritis. Formula IV gradually restored Jeanne’s health so much that several years later her blood work showed no trace of the rheumatoid factor. Meanwhile Fred started sharing Formula IV with everyone because he was so excited about the improvements he was witnessing in Jeanne.
Mr. Pickett opened his own manufacturing facility and testing equipment including an artificial stomach. Neo-Life holds a pharmaceutical license so as to keep standards high in the manufacturing of all Neo-Life products. Supplement manufacturers are not required by law to hold a pharmaceutical license but this was a choice of integrity that is still held by the company today. All raw materials are held to the highest standards and thoroughly tested for any impurities.
Mr. Pickett was still very active in Neo-Life when we joined the company in 1985 and we have had the privilege of meeting and visiting with him personally. When Mr. Pickett chose to retire, he turned the company over to 2 international business men who had the same values and integrity that he himself held. These 2 men were brothers, Jerry and Bob Brassfield. They owned 2 companies, Golden and Diamite. They merged those companies with Neo-Life and have expanded into over 50 countries around the world. At that time the name was changed to GNLD (Golden Neo-Life Diamite).
The exclusive, unique formula ‘Tre-en-en’ is still the core foundation product of GNLD. Tre-en-en is available in several GNLD products as well as a Tre-en-en stand alone: Pro Vitality, Pro Vitality with Formula IV Plus, Formula IV, Formula IV Plus, Premium All-Purpose Protein, Daily Vitality Pack – Sports 30, Daily Vitality Pack – Stress 30, Daily Vitality Pack – Active 40+, Vita-Squares Chewable Multivitamin, and Liqui-Vite Multivitamin.
Tre-en-en is a tested formula. It was originally tested on both sick people and also on athletes showing remarkable benefits for both the sickest and the healthiest. In 1962 a study was conducted on rats in response to the FDA’s challenge to health claims. The results of this study were very impressive showing the endocrine benefits on even the well-nourished. Another study was done in 1987 that showed an increase in adrenal activity of 175%, estrogenic activity increased 234%, and androgenic activity increased 155%. It also showed an increase in overall growth and development, cardiovascular development, and nutrient utilization efficiency.
So I can boldly state that Tre-en-en is the world’s best supplement for chronic fatigue. It replenishes the important lipids and sterols that are missing from our diets. It supplies the nutrients food processing strips from whole grains. It supplies nutrition at the cellular level by actually feeding each individual cell. It allows the cells to get rid of trapped toxins. It helps your body actually utilize more nutrition from the food you eat.
Is your body actually using all the nutrients you eat? Take the guess work out and supplement with Tre-en-en on a daily basis. It is the world’s best, most needed supplement.

We'd love to hear your thoughts on today's post! Please take a quick moment and leave your comments and/or questions below in the comment section.

Thank you!


  Pat is a Health, Fitness, and Nutrition Coach. 

Pat has been married to the same man for over 51 years, is the mother of 3 adult children, and gramma to 8 grandchildren.  Growing up in the country gave her a head start to living a healthy lifestyle.  This gramma became interested in nutrition as a mother and for the past 27 plus years she has specialized in teaching others the importance of good nutrition.  Challenges along the road have been many; her father overcoming congestive heart failure with nutrition, her husband's battle with GERD and avoiding a major heart attack, her daughter's battle with a brain tumor, her grandson beating Hodgkin's Lymphoma, her mother's stage 4 lung cancer, her mom-n-law's dementia, and others.  Her goal is to help others have the BEST REAL HEALTH possible and slow the aging process.  The products Pat has personally used since 1985 are featured at

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Comments on this entry are closed.


1 Henry November 8, 2020 at 8:06 pm

I’m new here and I’m suffering from IBS . (That’s iritatble bowel syndrome) I’m experiencing constant fatigue stamach pains and constipation. Can tre en en supplement help? A friend of mine have asked me to try this product for fatigue.

2 Petronila nwani October 31, 2019 at 2:25 pm

I be been taking Tre en en for 2wks plus now,honestly speaking Tre en en is the best. From petronila

3 James Muga August 29, 2019 at 1:39 am

I am currently taking High blood pressure medicine which I started 7 years ago. I need your advice

4 Emmanuella Ayuvea August 8, 2019 at 1:50 am

Woaw so amazing still a new comer

5 Matt May 28, 2019 at 11:38 pm

You need to take it 3 times a day to see strong benefit

6 Pat Moon June 4, 2019 at 10:39 am

You are absolutely correct, Matt. Tre-en-en gives its best results when taken 3 times a day.

7 Lilian Shongwe February 23, 2018 at 8:53 am

Lilian Pat, someone introduced the product to me a week before and It was so interested. I’ve never heard of TRE-EN-EN before.

8 Pat Moon April 1, 2018 at 4:03 pm

Tre-en-en was originally included in our basic Formula IV in 1958… a few years ago it was offered separately from the original vitamin/minerals included in Formula IV. You would be receiving it in our New Provitality Plus…

9 Richelle November 23, 2017 at 9:45 am

I have been taking tre en en and formula 4 and still tired. Any recommendations?
I also take super b and c

10 Pat Moon December 11, 2017 at 8:10 pm

Hello Richelle, Are you in the USA? If so, I would suggest you take ProVitality+ and drink at the NeoLife Shake. The best way to do that is to join the NeoLife Club and have the Breakfast Pack put on Auto Ship. Then you will receive a month’s supply of ProVitality+ and NeoLife Shake. Let me know if that helps… I believe it will. Here is the link to join the Club
Thanks for your question. Feel free to ask more.

11 QueenEstyPearl October 2, 2017 at 4:00 pm

Happiness can’t be much than being a partner with this great family of natural nutrients n vitamins. To me it is health, wealth n lifestyle..
I’m alive n awake jare.
Tnx tnx

12 Mirram July 10, 2017 at 3:26 am

I have just joined the Neo-life family

13 Samuel June 3, 2017 at 12:11 am

Itz nice be a member of gnld and a benefit of tre -en-en,am a new partner,but a friend of mine,discuss his health issue with me, his having a growth/moving object around his private part,Mrs pat what can he use 

14 Mary Sutton December 5, 2016 at 9:42 am


I have had Chronic Fatigue Syndrome since 1987. Well, gradually I have gotten better, but am experiencing a real dip in energy level.  I have started Tree-En-En, taking 2 pills a day after an Adrenal Fatigue conference online.  So far, no difference. Should I up this to 3 pills,etc. ?  I take many other Shaklee vitamins and don't want to eliminate these at this time.  Any guidance would be helpful.


Mary Sutton

15 Pat Moon April 6, 2017 at 9:19 pm

Hello Mary,

I am sorry I missed seeing your question back in Dec. I hope you are feeling better by now. To answer your question, Yes, you could easily up your Tre-en-en to 3 per day. I have taken that many on occasion. I understand you are taking Shaklee vitamins. Would it be possible for you to tell me what your symptoms are? Chronic Fatigue Syndrome can have a variety of symptoms. It is possible a digestive issue could be at the base of your issues. Digestion is often a very common problem in CFS. In that case, I suggest you could try some digestive aid supplements such as NeoLife's Beta-Gest, Enzymes, and Acidophilus Plus. I will be watching for your response or feel free to contact me directly at

Many your health improve soon.


16 Are Muizdeen Ayodele October 16, 2016 at 3:17 pm

Wow, really can't express how delighted I was on coming across this blog. I'm a new member of the Neo-Life family, this article not only gave me an indepth insight into the genesis of the fantastic 3 in 1 product of TRE EN EN it also informed of the very fantastic function of lipid and stereol.

I'm informed and very enthusiastic. Thanks Pat. 

17 Pat Moon April 6, 2017 at 7:49 pm

Welcome to a great company. NeoLife products are the very best.

18 Andrej Sagaidak April 17, 2016 at 2:39 pm

Seriously, I never knew of it till now. But Pat, you helped me a lot sharing such useful info with us!

– Andrej

19 Pat Moon August 4, 2016 at 8:01 pm

Please feel welcome to ask questions. I am here to help you more. Thank you for visiting my blog and commenting.

20 Phindile Radebe June 23, 2015 at 7:22 am

I like to encourage everyone to use GNLD product, i am a full member for +_ five years i've ordered different supplement, it works like BOM., i am 48 years old but you cant say i look young and beautiful and healthy, people must stop waisting money on something that they dont benefit  on,  rather use this product they are little bit expensive but your life will be better forever, i stated using this product after attended workshop first, thats where i join and stated to  study everything different product,  and i understand everything about them, i even order without looking to the catalogue i know them all, because i love GNLD with all my heart thank you MGP Radebe Heilbron.             

21 Pat Moon August 4, 2016 at 7:59 pm

You are so wise to use GNLD products…. they are the very best!

22 Albert Saligumba May 13, 2014 at 10:46 am

I have my personal interest of your Tre – En — En   product .   So I can boldly state that Tre-en-en is the world’s best supplement for chronic fatigue. – See more at:  I thank you and god Bless.

23 Pat Moon May 14, 2014 at 4:46 pm

Hello Albert,

I’m so thankful you are sharing your personal success with Tre-en-en and chronic fatigue. It is an amazing supplement.

Thank you and God’s special blessings to you.


24 Victor Ordu April 3, 2013 at 9:04 am

Dear Pat,
Finding this blog is the best thing to happen to me today. Tre-En-En has changed my life by improving my health and 'dragging' me in the business world (something I never dreamed of ever doing). Thanks for the generous post!


25 Pat Moon April 4, 2013 at 9:51 am

Nice to meet you, Victor. It is always so good to connect with fellow Neo-Lifer’s (GNLD). It is absolutely wonderful that Tre-en-en has changed your life and also that it drug you into our business world. I visited your site and see that you are a doctor and was troubled by your own health problems. It is great that your wife’s friend accepted your challenge to prove her wrong.. a wonderful testimony to the power of Tre-en-en. How did you happen to find my blog?

26 Anita January 30, 2013 at 3:09 pm

Thanks Pat for always sharing such educational and informative content!

27 Pat Moon February 5, 2013 at 5:39 pm

Anita, thanks for taking time to read my blog. My hope is that someone will be able to gleam something helpful.

28 Helena Bowers September 17, 2012 at 3:20 pm

Very interesting post Pat! I love to hear the historical background behind the product. This sounds like to could be of great benefit to many people.

29 Pat Moon September 19, 2012 at 9:23 am

Hi Helena,
The history of the product Tre-en-en is really the history of our company GNLD. It is an important story to really understand how the products & company came to be able to help people. Yes, many people can receive benefit from Tre-en-en.

30 Sharon O'Day September 16, 2012 at 11:54 pm

Fascinating information, especially within its historical framework.  Thanks, Pat, for sharing it.  With all the chronic fatigue we hear about these days, oh but that the world of allopathic medicine would look beyond its nose and recommend valuable (and effective) supplements to its patients.

31 Pat Moon September 17, 2012 at 5:47 pm

Hi Sharon,
It is so great to have friends stop by to take a look at the information on my blog. Chronic fatigue and other immune dysfunction diseases are all around us and could benefit so much from basic good nutrition. Of course, basic good nutrition can definitely reduce the risk of being burdened with health breakdown in the first place. My mother’s oncologist is very supportive of her extensive supplement program and actually stands amazed at how well she is doing in month 9 after being diagnosed with the stage 4 lung cancer.

32 Norma Doiron@Where Aspiring/Budding Business Owners Start, Grow & Strenghten Their Online Business September 12, 2012 at 11:00 am

Interesting product.  Never heard of it till today; I will refer if I know someone in need! 🙂

33 Pat Moon September 17, 2012 at 5:40 pm

Hi Norma, I’m so happy you visited my blog site.
Also, I’m glad I was able to introduce you to Tre-en-en and Formula IV. They are unique and so amazing in maintaining and/or rebuilding health. Products everyone can benefit from using. Always appreciate referrals.

34 Nisha Naik September 11, 2012 at 9:09 pm

What an interesting post! I had never heard of this supplement before. There are so many options better than traditional medicine.

35 Pat Moon September 17, 2012 at 5:37 pm

Welcome to my site, Nisha.
Many people have not heard of Tre-en-en or Formula IV but they need to know about them as they are so beneficial to basic good health. Yes, people with compromised health issues can benefit from these basic nutrients and that is important but healthy people can more easily stay that way with these supplements.

36 Lisa Frederiksen - September 11, 2012 at 6:56 pm

Wow – I'd never heard of this — thank you for sharing what sounds to be an amazing supplement!

37 Pat Moon September 17, 2012 at 5:32 pm

Lisa, yes, Tre-en-en is an unique and amazing supplement. As my article said it has been available since 1958 but many people have still not heard of it… that is my mission… to get the word out so people can experience the wonderful benefits from taking Tre-en-en or one of the partner products… personally I have used these products since 1985.

38 Sherie September 11, 2012 at 1:15 pm

This sounds really interesting, Pat…is this supplement considered gluten free? 

39 Pat Moon September 17, 2012 at 5:22 pm

Hi Sherie,
Yes, Tre-en-en is a very interesting and beneficial supplement for most people. Our Tre-en-en supplement does contain some gluten however our Formula IV is considered Gluten Free (below the 20 parts per million limit.) We have worked with these products since 1985 and have never had anyone experience a problem because of the gluten. When someone suspects or knows they have a sensitivity to gluten, we have them start very slowly with Formula IV and gradually build up to the suggested daily amount. The benefits of the tre-en-en formula actually contribute to giving the body the tools to utilize and use nutrients as well as rebuild from health issues.
Sherie, are you gluten intolerant?

40 Angie M Jordan September 11, 2012 at 1:07 pm

It is very interesting.  I have never heard of this before.  Thank you for the helpful information! 

41 Pat Moon September 17, 2012 at 4:19 pm

Thanks for reading my blog, Angie. Yes, Tre-en-en is a very interesting supplement and more people need to know about it. It is a supplement that everyone can benefit from taking to either maintain their good health or rebuild their health.

42 Barbara J Peter September 11, 2012 at 12:19 pm

this is so interesting Pat. I know that we have to have the right fuel in our body to run properly. I will remember this so anyone I know with this condition. 

43 Pat Moon September 17, 2012 at 4:11 pm

Barbara, thanks for your interest. You are so right, we have to have the right fuel in our body for it to run properly. Actually, the Tre-en-en is a very good basic supplement for everyone, not just for someone whose health has deteriorated to the point of chronic fatigue or some other illness. It’s a great energy booster as well as keeping your body running top notch.

44 Jenny Shain September 10, 2012 at 11:55 pm

Wow, I've never heard of this! I can't wait to hear what my naturalpath says about it! I'm learning so much! Thank you for the wealth of information. Such a helpful site, Pat!

45 Pat Moon September 17, 2012 at 4:06 pm

Jenny, please let me know what your naturalpath has to say about Tre-en-en. If they haven’t heard of it, they might want to consider making it part of their product line as everyone can benefit from this wonderful supplement. It is only available through a GNLD distributor like myself or becoming a distributor. I appreciate your interest in my information. Thanks.

46 Ron Cross September 10, 2012 at 7:16 pm

I had never heard of it either Pat! But as usual, I learn something new whenever I come here. Great info!

47 Pat Moon September 17, 2012 at 3:59 pm

Hi Ron, Thanks for taking the time to check out my information. Like I told Claudia, it seems that we need to be more aggressive about getting the word out about Tre-en-en as everyone could benefit health wise from using it as a base supplement for ensuring the basics in nutrition.

48 Claudia September 10, 2012 at 6:59 pm

I've never heard of Tre-en-en. I believe in whole foods supplements and not synthetic. This sounds like a great product. As always, great informative article Pat.

49 Pat Moon September 17, 2012 at 3:55 pm

Claudia, I believe Tre-en-en seems to be a well kept secret that needs to be spread. Tre-en-en is a trademark name for GNLD (Neo-Life)’s core product and is only available through a GNLD Distributor like myself. You will not find it in stores. We have used these supplements since 1985 because of the quality whole food source. I’ve looked at many other supplements over the years but never found any that are produced to the standard of Neo-Life products by GNLD.

50 Olga Hermans September 10, 2012 at 12:15 pm

Pat, you always give us such rich content. I know somebody who might be interested in this product Tre-en-en; I will give him this article…thanks for keeping us informed!

51 Pat Moon September 17, 2012 at 3:45 pm

Thanks, Olga. I appreciate the referral.

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